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Previously, people that were taking Cardarine alone experienced a gradual decrease in their fat cells, but they also had to grapple with the fact that they would also be losing some musclemass, too. "We knew that exercise could help increase HDL, but we didn't know how much or what the exact effect was," says Dr. Hennig, who conducted the research with colleagues at Brigham and Women's Hospital and Harvard's Brigham and Women's Medical Center. "We knew that exercise had helped with weight loss and a decrease in body adiposity, but it hadn't been well studied in people taking Cardarine." The results, which were presented today at the American Heart Association's Scientific Sessions 2011 conference in San Diego, suggested that if Cardarine is taken with a meal, it could affect the process of weight loss, even though it didn't change whether people were losing fat or burning calories, Dr. Hennig explained. A low-fat diet could provide a boost The scientists studied three groups of people: men between 45 and 68 years old who lost 10 percent of their body weight and lost the most in the first 12 weeks after the diet plan was adopted and then lost another 10 percent each time after 12 weeks. They found that the participants who'd begun taking a low-fat diet gained fat and lost muscle as a direct result of the Cardarine regimen, even after adjusting for the fact that they were losing weight. "That means that if you're on a low-fat diet, you're going to gain some fat," Dr. Hennig explains. "It's possible that those individuals were taking a dose of exercise in their diet plan that wasn't quite enough to stimulate muscle loss." The researchers also looked at the effects of Cardarine on the metabolism, showing that it didn't increase or decrease food consumption. They suspect that that could be because the high fiber was absorbed into the body more quickly than the carbohydrate in Cardarine, while the fiber could also be metabolized more efficiently so it didn't contribute to waste products such as lactic acid that build up during the process. "We're very pleased with the outcome" Dr. Hennig said the study is still preliminary, but he thinks it will help guide diet plans when health authorities are weighing the benefits and risks of low-fat diets or other kinds of exercise intervention. The researchers are currently working on a followup study to evaluate the effects of taking Cardarine as part of the low-fat diet. "In the interim, there are some really cool applications of Cardarine," Dr. Hennig notes. "It could be used in the treatment Related Article: